Arthrosamid Knee Pain Injection

iPAAG Knee Pain Injection

Arthrosamid®, an intra-articular polyacrylamide hydrogel injection (iPAAG), is a new type of treatment for knee osteoarthritis that offers patients an effective alternative to the currently available therapies. The treatment involves an injection into the knee that provides effective relief from the pain associated with knee osteoarthritis. Osteoarthritis generally occurs when the cartilage (the one that cushions the bone ends in your joints) gradually deteriorates. Arthrosamid® is a knee pain injection that is based on an innovative non-biodegradable hydrogel technology.  It is 97.5% water with 2.5% being a cross-linked polyacrylamide backbone meaning once it has the properties to make it a longer lasting solution that other typical treatments for osteoarthritis pain. When injected into the knee, Arthrosamid® cushions the joint in a different way in comparison to standard injections and reduces pain. It works on the synovium and reduces inflammation, providing safe and sustained relief, all with one injection.

How Does Arthrosamid® Work?

Once the iPAAG is injected into the inner joint cavity to treat osteoarthritis, it restores viscosity within the synovial fluid, improving lubrication and cushioning of the joint. Arthrosamid® also integrates into the synovium of the inner joint capsule creating a cushion-like effect. This cushioning and lubrication tackles the pain inducing effects of osteoarthritis that are caused by the degeneration of cartilage. The pain relief injections are a single dose solution to pain in the knee caused by osteoarthritis.

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How does Arthrosamid® differ from other injectable knee pain treatments?

Arthrosamid® is different from Viscosupplement injections for the knee such as hyaluronic acid (HA), platelet-rich plasma (PRP) and regenerative stem cell therapy. Unlike these treatments, Arthosamid® is a non-degradable hydrogel that can efficiently cure knee osteoarthritis. It has the properties to lubricate and cushion for longer.

Unlike the other treatments, Arthosamid® also has the ability to become an integrated part of the soft synovial tissue in the joint capsule, leading to longer-lasting pain relief and giving the ultimate solution to knee osteoarthritis.

In a number of clinical trials with Arthrosamid®, there were no serious side effects related to the hydrogel. The most commonly reported side effects were mild to moderate injection site pain and swelling, which were generally transient in nature. The overall safety profile of hydrogel has been established over the last 20 years with its use for various indications in the body.

before arthrosamid
3 months after arthrosamid
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Other Treatments

In addition to aiding osteoarthritis, we offer biological surgery, knee meniscus, salvage treatment for cartilage damage for the whole body, cartilage supplements, and scaffold regeneration.

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